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Daxxify

More time with less expression lines

Premier Dermatology & Aesthetics is proud to be the first practice in Northwest Arkansas to offer DAXXIFY, the newest neurotoxin.

DAXXIFY™ is FDA approved to help smooth moderate to severe lines between the brows. It is the only long-lasting frown line treatment powered by a peptide with results that last on average 6 months and up to 9 months for some.

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About DAXXIFY

DAXXIFY is the only long-lasting, peptide-powered frown line treatment and the first innovation of its kind in over 20 years. It is manufactured in California and is the only prescription frown line treatment made in the United States.

Stay smoother longer with DAXXIFY. On average, results last 6 months and up to 9 months for some patients. You may also see results sooner - as early as the next day after treatment, and typically within two days.

In 2002, physicians and entrepreneurs founded a start-up in Silicon Valley, California to explore the use of peptides in biologics for different therapeutic uses. Their goal was to utilize peptides to transport biologics, typically large molecules, through the skin.

The initial idea was to formulate botulinum toxin type A, the active ingredient in DAXXIFY™, with a peptide to see if it could be applied topically to the skin to treat crow’s feet wrinkles. Through this process, scientists discovered that the formulation was optimally administered through injection. Several clinical studies were created to determine the correct dose for an injectable product that would treat frown lines.

All frown line treatments require a special ingredient to stabilize botulinum toxin A, the protein responsible for helping smooth moderate to severe frown lines. For instance, BOTOX® Cosmetic uses human serum albumin (HSA), a blood product, as its stabilizer. Dysport®, another frown line treatment, uses cow’s milk protein in addition to HSA. DAXXIFY™ is unique because it is the only formulation that uses a novel peptide as a stabilizer and does not contain human or animal byproducts.

BEFORE & AFTER

Expression Lines

Neuromodulators - such as Botox Cosmetic, Jeuveau, DAXXIFY, and Dysport - are well-recognized injectable treatments for obvious reasons...they work. Once injected into facial muscles, fine lines and wrinkles relax. The result is a well-rested, younger looking version of yourself. The most commonly treated areas are the forehead, between the brows (glabella), and around the eyes (crow's feet). Fine lines that develop around the eye are often the first signs of aging.

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FAQs

How long has botulinum toxin type A been used in facial aesthetics?

Injectable wrinkle treatments containing botulinum toxin type A have been used to improve the look of moderate to severe frown lines for more than 20 years. The first FDA-approved treatment was BOTOX® Cosmetic, followed by Dysport®, Xeomin®, and Jeuveau®.

Although today’s wrinkle reducers all contain botulinum toxin type A, it’s important to know that no two treatments are alike and the doses cannot be interchanged with each other.
How is DAXXIFY™ different from other frown line treatments?

DAXXIFY™ is the only long-lasting frown line treatment powered by a peptide. Results last on average 6 months and up to 9 months for some.*

Other manufacturers use human serum albumin or cow’s milk protein to stabilize botulinum toxin type A, the active ingredient in injectable wrinkle treatments. DAXXIFY™ is the only formulation to contain a peptide and does not rely on human serum albumin or cow’s milk protein.
How is DAXXIFY™ different from facial fillers, also known as dermal fillers?

DAXXIFY™ minimizes the appearance of moderate to severe frown lines by temporarily relaxing the underlying muscles that cause these wrinkles. DAXXIFY™ is a long-lasting botulinum toxin type A treatment with a novel peptide.

Facial fillers, also known as dermal fillers, are typically made of hyaluronic acid and are used to add volume, fullness, and structure to areas of the face. They can help contour cheekbones, soften lines around the nose and mouth, and volumize lips. Dermal fillers target volume loss rather than muscle-related wrinkles.
Will I see results quickly?

You may see results with DAXXIFY™ as early as the next day after treatment, and typically within two days.
Is DAXXIFY™ for me?

Is your frown line treatment not lasting as long as you would like? If so, DAXXIFY™ could be the solution for you. Discuss your treatment goals with your aesthetic services provider.
How do botulinum toxins work?

Botulinum toxins are biologics, produced from a bacterium called Clostridium botulinum. They are used to inhibit the transmission of specific chemical signals from nerves, primarily those signals that cause muscular contractions. Botulinum toxin type A injections temporarily relax the facial muscles that cause wrinkles between the brows, reducing their appearance.

DAXXIFY™ is the only FDA-approved, long-lasting frown line treatment (neuromodulator) to help smooth moderate to severe lines between the brows, lasting on average 6 months and up to 9 months in some.
Does DAXXIFY™ work on all skin types?

The safety and efficacy of DAXXIFY™ is well established, with more than 20 years of research. In fact, DAXXIFY™ has been studied in the largest ever phase 3 clinical trial program conducted for a frown line treatment and included more than 2,400 people across different ages and with different skin types. There were no notable differences in how DAXXIFY™ performed in clinical trial patients with varying skin types.
I have an event coming up in 2 weeks and want to try DAXXIFY™. Is now the right time to get treated?

You may see results with DAXXIFY™ as early as the next day after treatment, and typically within two days. You should see noticeable results within a two-week time frame. You may experience mild injection-related bruising. In most cases, bruising heals within a few days after injection.
How should I prepare for my DAXXIFY™ treatment?

Ask your aesthetic provider for pre-treatment instructions prior to your DAXXIFY™ appointment.

A list of common avoidances before treatment include, but are not limited to:
Retin-A
Blood thinners
Muscle relaxants
Fish or oils rich in omega 3
Allergy medication
Topical steroids
Sleep medications and supplements
Aspirin
St. John’s Wort
Supplements containing Vitamin E
Ibuprofen
Does getting DAXXIFY™ hurt?

DAXXIFY™ injections are typically performed with a small needle, so you should only experience minimal discomfort during treatment. People treated with frown line treatments say the injection feels like a pinch.

There is a possibility that the area around the injection site will swell, turn red, and cause pain or tenderness from the injection itself; however, these side effects are typically very minor and go away after a few hours or days.
How do frown lines form?

Several factors contribute to the formation of facial lines. Decreased collagen production, cellular changes, genetics, environmental damage, and sun damage may all play a role.

Facial lines are also formed by repeated muscle contractions such as frowning, squinting, or raising the eyebrows. These facial expressions cause the skin to furrow and fold, which eventually leads to the formation of wrinkles.

DAXXIFY™ works below the skin’s surface to temporarily reduce the underlying muscle activity responsible for moderate to severe frown lines.